Signs and Evidence

Making clinical sense of scientific data

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Beware of the limitations of this tool

Hypothyroidism

Calculated pretest probability: 3.82 %
Relevant inclusion criteria: All adults 

Anamnesis

1Sweating
2Hair loss
3Swallowing complaints
4Constipation
5Fatigue - tired
6Palpitations
7Cough
8Headache


Clinical signs

9Cool skin
10Wheezing

To further investigations





Sources used:

1.Carle A et al. Hypothyroid symptoms and the likelihood of overt thyroid failure: a population-based case–control study. Eur J Endocrinol. 2014 Nov;171(5):593-602
2.Zulewski H et al. Estimation of Tissue Hypothyroidism by a New Clinical Score: Evaluation of Patients with Various Grades of Hypothyroidism and Controls. The Journal of clinical endocrinology and metabolism. 82. 771-6
3.Abu-Helalah M et al. A randomized double-blind crossover trial to investigate the efficacy of screening for adult hypothyroidism. Journal of Medical Screening 2010; 17(4):164-69
4.Madariaga AG et al. The Incidence and Prevalence of Thyroid Dysfunction in Europe: A Meta-Analysis. The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 3, 1 March 2014, Pages 923–931