Signs and Evidence

Making clinical sense of scientific data


Beware of the limitations of this tool

Prostate cancer

Calculated pretest probability: 3 %
Relevant inclusion criteria: Age 50 - 78 

Clinical signs

1Digital rectal exam abnormal

To further investigations

Sources used:

1.Driel MF et al. Fysische diagnostiek - Rectaal toucher. NtvG 18-03-2002
2.Mistry K et al. Meta-Analysis of Prostate-Specific Antigen and Digital Rectal Examination as Screening Tests for Prostate Carcinoma. J Am Board Fam Med March 1, 2003 vol. 16 no. 2 95-101
3.Adhyam M et al. A Review on the Clinical Utility of PSA in Cancer Prostate. Indian J Surg Oncol. 2012 Jun; 3(2): 120–129
4.Ankerst DP et al. Sensitivity and specificity of prostate-specific antigen for prostate cancer detection with high rates of biopsy verification. Arch Ital Urol Androl. 2006 Dec;78(4):125-9
5.Yunusa B et al. Determination of the sensitivity and specificity of serum prostate-specific antigen in the diagnosis of prostrate cancer in Kano, Northwestern Nigeria. Niger J Basic Clin Sci 2017;14:88-91
6.Blanker MH et al. Prevalentie van prostaatkanker gelijk bij mannen van 50 jaar of ouder met en zonder mictieklachten. Ned Tijdschr Geneeskd. 2003;147:973-8