Signs and Evidence

Making clinical sense of scientific data

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Leukocytosis (> 10000 / ml)

Cholecystitis
 Positive likelihood ratio
1.47 ( Trowbridge RL et al. )
(average) 1.47
Negative likelihood ratio
0.65 ( Trowbridge RL et al. )
(average) 0.65
Appendicitis
 Positive likelihood ratio
2.23 ( Al-gaithy Zuhoor K et )
1.60 ( Saaiq M et al. )
1.89 ( Dahmardehei M et al. )
2.91 ( Kamran H et al. )
(average) 2.16
Negative likelihood ratio
0.35 ( Al-gaithy Zuhoor K et )
0.21 ( Saaiq M et al. )
0.26 ( Dahmardehei M et al. )
0.32 ( Kamran H et al. )
(average) 0.29
Diverticulitis
 Positive likelihood ratio
11.28 ( O'Connor ES et al. )
1.60 ( Stefánsson R et )
(average) 6.44
Negative likelihood ratio
0.24 ( O'Connor ES et al. )
0.33 ( Stefánsson R et )
(average) 0.29


Sources used:

1.Trowbridge RL et al. Does This Patient Have Acute Cholecystitis? JAMA, January 1, 2003—Vol 289, No. 1 80-86
2.Al-gaithy Zuhoor K et al. Clinical value of total white blood cells and neutrophil counts in patients with suspected appendicitis: retrospective study. World Journal of Emergency Surgery : WJES. 2012;7:32
3.Saaiq M et al. Diagnostic Accuracy of Leukocytosis in Prediction of Acute Appendicitis. Journal of the College of Physicians and Surgeons Pakistan 2014, Vol. 24 (1): 67-69
4.Dahmardehei M et al. Diagnostic Value of Leukocytosis, ESR and CRP in Patients with Suspected Acute Appendicitis. Zahedan J Res Med Sci 2013 Jul; 15(7): 59-63
5.Kamran H et al. Role of total leukocyte count in diagnosis of acute appendicitis. J Ayub Med Coll Abbottabad 2008;20(3)
6.O'Connor ES et al. Outpatient Diverticulitis: Mild or Myth? J Gastrointest Surg. 2012 Jul; 16(7): 1389–1396
7.Stefánsson R et al. Diverticulitis of the sigmoid colon. Acta Radiologica (1997) 38:2, 313-319