Signs and Evidence

Making clinical sense of scientific data


Beware of the limitations of this tool


Calculated pretest probability: 21.45 %
Relevant inclusion criteria: Primary headache 


4Exacerbation by physical activity
5Unilateral pain
6Throbbing or pulsating pain
7Lacrimation during headache

Sources used:

1.Smetana GW et al. The Diagnostic Value of Historical Features in Primary Headache SyndromesA Comprehensive Review. Arch Intern Med. 2000;160(18):2729-2737
2.Uluduz D et al. Cranial autonomic features in migraine and migrainous features in cluster headache. Arch Neuropsychiatr 2016; 53
3.Sedlic M et al. Epidemiology of Primary Headaches Among 1,876 Adolescents: A Cross-Sectional Survey. Pain Medicine 2016; 17: 353–359
4.Kim BK et al. Prevalence and Impact of Migraine and Tension-Type Headache in Korea. J Clin Neurol. 2012 Sep; 8(3): 204–211
5.Stovner LJ et al. Prevalence of headache in Europe: a review for the Eurolight project. J Headache Pain (2010) 11:289–299