Signs and Evidence

Making clinical sense of scientific data


Beware of the limitations of this tool

Allergy and Immunology

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Sources used:

1.Kim H et al. Validating childhood symptoms with physician-diagnosed allergic rhinitis. Ann Allergy Asthma Immunol 108 (2012) 228 –231
2.Salkind AR et al. Is This Patient Allergic to Penicillin? An Evidence-Based Analysis of the Likelihood of Penicillin Allergy. JAMA, May 16, 2001—Vol 285, No. 19. 2498 - 2505
3.Sodhi M et al. Is it safe to use carbapenems in patients with a history of allergy to penicillin? Journal of Antimicrobial Chemotherapy, Volume 54, Issue 6, 1 December 2004, Pages 1155–1157
4.Siles RI et al. Allergy blood testing: A practical guide for clinicians. Cleveland Clinic Journal of Medicine. 2011 September;78(9):585-592
5.Vidal C et al. Evaluation of the phadiatop test in the diagnosis of allergic sensitization in a general adult population. J Investig Allergol Clin Immunol. 2005;15(2):124-30
6.Tschopp JM et al. Current allergic asthma and rhinitis: diagnostic efficiency of three commonly used atopic markers (IgE, skin prick tests, and Phadiatop®). Allergy. 1998 Jun;53(6):608-13
7.Bauchau V et al. Prevalence and rate of diagnosis of allergic rhinitis in Europe. Eur Respir J. 2004 Nov;24(5):758-64
8.Shah NS et al. Documenting Penicillin Allergy: The Impact of Inconsistency. PLoS One. 2016; 11(3): e0150514
9.Albin S et al. Prevalence and Characteristics of Penicillin Allergy in Urban Adults. J allergy clin immunol volume 131, number 2