Signs and Evidence

Making clinical sense of scientific data

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Constipation

Hypothyroidism
 Positive likelihood ratio
2.29 ( Carle A et al. )
3.20 ( Zulewski H et al. )
(average) 2.75
Negative likelihood ratio
0.74 ( Carle A et al. )
0.61 ( Zulewski H et al. )
(average) 0.68
Small bowel obstruction
 Positive likelihood ratio
8.80 ( Bohner H et al. )
(average) 8.8
Negative likelihood ratio
0.60 ( Bohner H et al. )
(average) 0.6


Sources used:

1.Carle A et al. Hypothyroid symptoms and the likelihood of overt thyroid failure: a population-based case–control study. Eur J Endocrinol. 2014 Nov;171(5):593-602
2.Bohner H et al. Simple data from history and physical examination help to exclude bowel obstruction and to avoid radiographic studies in patients with acute abdominal pain. Eur J Surg. 1998 Oct;164(10):777-84
3.Zulewski H et al. Estimation of Tissue Hypothyroidism by a New Clinical Score: Evaluation of Patients with Various Grades of Hypothyroidism and Controls. The Journal of clinical endocrinology and metabolism. 82. 771-6