Choose a clinical sign Abdominal MassAbdominal painAbsence of coughActive extension causing painAnginaAnkle reflex abnormal AnorexiaAnterior drawer testAphasia - everApley's testAsymmetryBack painBedwettingBilateral plantar numbnessBowel sound decreasedBowel sounds increasedBreathing frequency > 40 / minBrudzinski's signBulging tympanic membraneButtock PainCalf wastingCentral obesityCervical adenopathyCheesy dischargeChest-wall tendernessChillsClock drawing testClosed fist signCloudy tympanic membraneColic painConstipationCool skinCoughCrackles Cut tongueCyanosisDecreased breath sounds on examinationDiameter > 6 mmDiarrheaDiastolic murmurDifference in calf diameterDigital rectal exam abnormalDiplopiaDiscoloured skinDrop arm testDullness on percussionDyspneaDysuriaEar painEdema lower extremitiesEgophonyEichhoff's testEmpty can testEnlargingEpigastric painExacerbation by physical activityExertional PainExudatesFamily history of allergic diseasesFAST testFatigue - tiredFemoral bruitFEV1 < 80FeverFlexural complaintsFull can testGenital ulcerGlabella tap testGroin painHair lossHawkins testHead turningHeadacheHeart rate > 100 BPMHematuria - macroscopicHemiparesis - everHirsutismHypalgesia in median nerve territoryIntercostal recessionIntermittent claudicationIrregular borderIrregular pulse - palpatedItchingJaw claudicationJoint line tendernessJolt accentuationKernig's signLachman testLacrimation during headacheLeg sensation abnormalLimb jerkingLoss of balanceLymphadenopathy - anyMalignant diseaseMcMurray's testMicrographiaMigration of painMMSE < 27Morning stiffnessMurphy's signMyalgiaMyocardial infarction in historyNasal congestionNasal flaringNauseaNocturiaNocturnal paresthesiaNuchal rigidityObserved unresponsivenessOcular itchOral ulcerOther allergic diseasesPain in left armPain on motion in anklesPain on motion in DIPsPain on motion in elbowsPain on motion in hipsPain on motion in kneesPain on motion in MCPsPain on motion in PIPsPain on motion in shouldersPain on motion in wristsPain valgus stress 30°Painful arcPalatal petechiaePalpable pulse abnormalityPalpable thyroidPalpitationsPassive lumbar extension testPhonophobiaPhotophobiaPivot shiftPolakysuriaPosterior drawer testPostictal headacheProdromal tremblingPsoas signRadiating painRebound tendernessRecent immobilizationRecent surgeryRed tympanic membraneReporting history of this allergyRhinorrheaRight lower quadrant painRight upper quadrant painRigiditySeasonalityShuffling gaitSlump testSmokingSoap intoleranceSore throatSoresSplenomegalySpO2 < 90%SpO2 < 95%SputumSquat causing posterior painStraight Leg Raising testStriaeSwallowing complaintsSweatingSwelling in anklesSwelling in DIPsSwelling in elbowsSwelling in kneesSwelling in MCPsSwelling in PIPsSwelling in wristsSystolic murmurTemporal artery painThrobbing or pulsating painTinel's testTremorTrendelenburg testTwo or more colorsUlnar nerve compressionUnilateral painUnilateral paresthesia - everUrgency - mictionUrinary symptomsVaginal dischargeValsalva's maneuverVerbal fluency test < 15VomitingWalking heel-to-toe impairedWeak ankle dorsiflexionWHAT testWheezingWheezing on examinationXerosisYellow discharge

Murphy's sign

Murphy’s sign is performed by palpating the subcostal region during inspiration. If pain is elicited and the patient suddenly stops their inspiratory effort, a positive Murphy’s sign has been elicited.

Cholecystitis
	Positive likelihood ratio 2.80 ( Trowbridge RL et al. ) 5.00 ( Abraham S et al. ) 1.24 ( Hwang H et al. ) (average) 3.01	Negative likelihood ratio 0.50 ( Trowbridge RL et al. ) 0.40 ( Abraham S et al. ) 0.71 ( Hwang H et al. ) (average) 0.54

Sources used:

1.	Trowbridge RL et al. Does This Patient Have Acute Cholecystitis? JAMA, January 1, 2003—Vol 289, No. 1 80-86

2.	Abraham S et al. Surgical and Nonsurgical Management of Gallstones. Am Fam Physician. 2014 May 15;89(10):795-802

3.	Hwang H et al. Does ultrasonography accurately diagnose acute cholecystitis? Improving diagnostic accuracy based on a review at a regional hospital. Can J Surg. 2014 Jun; 57(3): 162–168