Signs and Evidence

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Murphy's sign

Murphy’s sign is performed by palpating the subcostal region during inspiration. If pain is elicited and the patient suddenly stops their inspiratory effort, a positive Murphy’s sign has been elicited.
Musana K et al. Murphy’s Sign. Clin Med Res. 2005 Aug; 3(3): 132
Cholecystitis
 Positive likelihood ratio
2.80 ( Trowbridge RL et al. )
5.00 ( Abraham S et al. )
1.24 ( Hwang H et al. )
(average) 3.01
Negative likelihood ratio
0.50 ( Trowbridge RL et al. )
0.40 ( Abraham S et al. )
0.71 ( Hwang H et al. )
(average) 0.54


Sources used:

1.Trowbridge RL et al. Does This Patient Have Acute Cholecystitis? JAMA, January 1, 2003—Vol 289, No. 1 80-86
2.Abraham S et al. Surgical and Nonsurgical Management of Gallstones. Am Fam Physician. 2014 May 15;89(10):795-802
3.Hwang H et al. Does ultrasonography accurately diagnose acute cholecystitis? Improving diagnostic accuracy based on a review at a regional hospital. Can J Surg. 2014 Jun; 57(3): 162–168